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The Immune Function in Children with Bronchiectasis study explored the suggestion that the immune system in children with bronchiectasis developed in a way that has made them susceptible to respiratory infections and chronic airway inflammation. This study aimed to provide information on the causes of the disease and the management of children with the illness.
The study identified eosinophilia in the airways of Indigenous children with chronic suppurative lung disease CSLD and bronchiectasis which has lead to changes in clinical management. It also found a dysfunctional cell mediated immune response to a common respiratory bacteria, non-typeable Haemophilis influenza, in children with CSLD.
Abstract adapted from Menzies School of Health Research
Menzies School of Health Research