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TROVE - Case control study of rotavirus vaccine effectiveness in the NT



This project aimed to evaluate the impact of rotavirus vaccination in both reducing hospitalisations in the Northern Territory (NT) for diarrhoea caused by rotavirus, and in reducing the causes of other types of diarrhoea.

Results of the project found that rotavirus vaccination reduced the incidence of rotavirus hospitalisation by 59% and the risk of all-cause gastroenteritis by 29%, however, rotavirus remains the single most common cause for gastroenteritis in the NT.

The study demonstrated the importance of a rotavirus vaccination program in the NT, and will guide the development of future vaccination programs.

Abstract adapted from Menzies School of Health Research


Menzies School of Health Research
John Matthews Building
Royal Darwin Hospital Campus
PO Box 41096
Casuarina NT 0811
Ph: (08) 8922 8196
Fax: (08) 8927 5187

Related publications

Snelling TL, Markey P, Carapetis JR, Andrews RM (2012)

Rotavirus in the Northern Territory before and after vaccination.

Microbiology Australia; 33(2): 61-63

Snelling TL, Andrews RM, Kirkwood CD, Culvenor S, Carapetis JR (2011)

Case-control evaluation of the effectiveness of the G1P[8] human rotavirus vaccine during an outbreak of rotavirus G2P[4] infection in Central Australia.

Clinical Infectious Diseases; 52(2): 191-199

Snelling TL, Schultz R, Graham J, Roseby R, Barnes GL, Andrews RM, Carapetis JR (2009)

Rotavirus and the Indigenous children of the Australian outback: monovalent vaccine effective in a high-burden setting.

Clinical Infectious Diseases; 49(3): 428-431


Last updated: 7 March 2014
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