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The Pneumococcal immunisation protection and awareness project (PIPPA) was a National Health and Medical Research Council (NHMRC) funded study that aimed to determine whether immunisation with 23vPPV (Pneumovax) generates an adequate immune response in Indigenous adults, and whether prior pneumococcal vaccination is a factor that could reduce the immune response.
The study recruited 300 people (Indigenous and non-Indigenous) aged 15-64 years and measured their immune response before and after the vaccine.
It was hoped that the study would contribute substantially to the immunogenicity evidence base for pneumococcal vaccine policy for Indigenous Australians and other high risk population groups receiving multiple dose of 23vPP.
The study found that repeated immunisation with the Pneumovax vaccine resulted in impaired immune response.
Abstract adapted from Menzies School of Health Research
Menzies School of Health Research
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